The Role of Diazepam in U.S. Medical Practice In the United States, diazepam is widely prescribed to manage conditions like anxiety, alcohol withdrawal, and muscle tension. Its sedative properties also make it useful as a preoperative medication to reduce anxiety before surgeries. Although diazepam is effective, its potential for abuse has led to strict regulation by the DEA. It is only available via prescription, and long-term use can lead to physical dependence, making it essential for healthcare providers to closely monitor its use.